viernes, 10 de julio de 2009

Medical 0.0.34 . It's all about standards

Medical: The Universal Health and Hospital Information System

Hello there

Medical version 0.0.34 has just been released !

The most important feature of this version is the addition of ICD-10-PCS.
The International Classification of Diseases tenth revision Procedure Coding System (ICD-10-PCS) will complement the already implemented ICD-10 coding for pathologies. This duple provides a very efficient way of coding for doctors and administrative personnel, making the data interchange between organizations very easy and with a common language, around the world.

In this version of Medical we have the 2009 ICD-10-PCS version, which contains 72589 medical procedures, from surgery to substance administration and monitoring. ICD-10-PCS is the replacement for ICD-9-CM.

In this way, Medical is pioneer by having already the two standard for diagnosis (ICD-10) and procedures (ICD-10-PCS) that are to be adopted by most institutions in the coming years.

This version also has major improvements in dealing with the queries of large tables, modifications on the surgery and patient evaluation and some bug fixes. Check the Changelog for all the modifications.

Check the wiki for the installation instructions at

Please file bugs and comments at the sourceforge portal (

Luis Falcon

PS: This version is considerably bigger than the previous ones, so give some time to the database import process :)

jueves, 9 de julio de 2009

Thoughts about H1N1, cytokine storm and public health decisions

Since the first fatalities related to H1N1 that affected young, healthy people, the cytokine storm theory was raised. And it makes sense. In many cases, after a couple of days, patients would develop severe pneumonia and die in a very short period of time.

The cytokine storm is a over-reaction of the immune system when trying to attack the invader ( in this case, the influenza virus ). The hiper-cytokinemia triggers a positive feedback vicious cycle, releasing a huge amount of pro-inflammatory messengers (Tumor Necrosis Factor - TNF -, and other Interleukins ).

These messengers signal leukocytes ( T-cells, neutrophils... ) to go to the site of infection. Since there is a over-reaction, the white cells action produce damage in the area of action. In the case of the H1N1, in the lung parenchyma.

Now, with several months that H1N1 is among us, and with the experience of the H5N1 (avian flu), in which cytokine storm was the cause of most deaths, my questions are :

- Do we have conclusive evidence (histo-pathological, serum TNF levels, ... ) that confirm a cytokine storm in some of the H1N1 patients ?

- Antivirals : They work by inhibiting the virus replication process, so they don't boost an immune reaction (which is good in this case).

Why don't give antivirals as a prophylactic measure ? This would minimize the initial immune reaction, and thus, prevent or minimize the possibility of the cytokine storm.

We also know that antivirals work best within the first 24 / 48 hours of symptoms. The idea is to avoid pneumonia in the first place. Medicine is about promotion and prevention, so we should avoid at all costs H1N1 complications. What I see is that in many cases, they wait until there is a serious condition related to the flu to start medicating. It just seems too bad-to-late to me...

- Government Improvisations : I feel like there is a lot of improvisation on the way that certain governments are dealing with this issue. In my personal experience, a couple of days ago my daughter got sick, with fever, sore throat and was negative to the strep test (was viral). When I knew that she was negative for strep, I asked for the antivirals and it was denied, since she was not part of the "risk group". This of course is not to blame the doctor, but the health officials.

I'm saying this because the same health officials were giving antivirals to everyone that had flu symptoms and, as a prophylactic measure, to their relatives. That was, in my opinion, the right way to go. Unfortunately, that decision lasted only for two days.

So, I had to spend these last two days in a paranoid state checking on my daughter evolution and hoping that it won't spread to his younger brother.

Why do I have the feeling that high government officials and their kids have the antiviral sitting close to them "just in case"... Anyways... better leave it here...

It would be great if any of you want to make comments or have extra information and shed some light on this subject.

Luis Falcon

miércoles, 8 de julio de 2009

Latin America gains momentum in Open Source

Great news for all of us open source activists in Latin America.

This year we have three projects "hechos en latinoamérica" that are finalist in sourceforge : Medical (Best Project for Government), Elastix (Best Project for the Enterprise) and Process Maker (Best Commercial Open Source and Best Visual Design)

I want to thank the community and, specially, the organizations like Free Software Foundation (FSF), and great guys like Jon "Maddog" Hall, who have been key for the adoption of the Open Source in Latin America (and worldwide).

Here is a picture from Debconf 2008 in Buenos Aires, Argentina, where I met with Jon and talked about the Medical project.